Shiitake Lentinula edodes Shiitake is best known as a culinary mushroom, but its medicinal contributions—especially for heart health—are substantial. Request a Quote Historical use Fruiting bodies used Culinary-medicinal in East Asia Known for Supporting cardiovascular health and cholesterol regulation Target areas Heart, blood vessels, immune system Active compounds Lentinan, eritadenine, polysaccharides Type Saprophytic Native to East Asia Other info One of the oldest cultivated mushrooms